Trimethoprim - Drug Information - Kaiser Permanente

Provides a summary of interactions with vitamins, herbs, and food

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Trimethoprim-Sulfamethoxazole Revisited - JAMA Network

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Unfortunately, the prevalence of resistant coliforms is increasing. 59,62-70 In the 1980s, trimethoprim resistance in E coli isolates from outpatient urine samples often reached 15% to …

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Assessment Of Typing Methods, Virulence Genes Profile And …

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1 day ago · Proteus mirabilis (P. mirabilis) is one of the most important causative pathogens associated with complicated urinary tract infections with a 20% incidence. For epidemiological …

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FAQs about Trimethoprim - Drug Information - Kaiser Permanente Coupon?

Does trimethoprim have side effects?

* Trimethoprim has side effects similar to those of sulfamethoxazole, but they are less common. (See also Overview of Antibiotics.) neural tube defects), such as spina bifida, are a risk. ...

How many metabolites does trimethoprim have?

Trimethoprim is metabolized in vitro to 11 different metabolites, of which, five are glutathione adducts and six are oxidative metabolites, including the major metabolites, 1- and 3-oxides and the 3- and 4-hydroxy derivatives. The free forms of sulfamethoxazole and trimethoprim are considered to be the therapeutically active forms. ...

Can I take sulfamethoxazole with food?

Follow all instructions closely. Take with or without food. Take with food if it causes an upset stomach. Take with a full glass of water. Take this medicine (sulfamethoxazole and trimethoprim tablets) at the same time of day. ...

Does trimethoprim/sulfamethoxazole affect breast milk production?

Trimethoprim/sulfamethoxazole is present in breastmilk. There is no information on the drug’s effects on milk production or the breastfed infant. Breastfeeding should be avoided during therapy because of the potential risk of bilirubin displacement, and associated brain damage (kernicterus) in the breastfed infant. ...

How long does sulfamethoxazole last?

The mean serum half-lives of sulfamethoxazole and trimethoprim are 10 and 8 to 10 hours, respectively. However, patients with severely impaired renal function exhibit an increase in the half-lives of both components, requiring dosage regimen adjustment (see DOSAGE AND ADMINISTRATION section). ...

Can trimethoprim and sulphonamide be used to treat chest infections?

Hughes DT The use of combinations of trimethoprim and sulphonamides in the treatment of chest infections. J Antimicrob Chemother. 1983;12423- 434 Google Scholar Crossref Gaskins JDHolt RJKyong CUWeart CWWard J Chemoprophylaxis of recurrent otitis media using trimethoprim/sulfamethoxazole. ...